| Item Type | Name |
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Concept
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Bacterial Outer Membrane Proteins
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Concept
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Bacterial Proteins
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Concept
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Fungal Proteins
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Concept
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DNA-Binding Proteins
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Concept
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Membrane Proteins
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Concept
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Protein Binding
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Concept
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Protein Conformation
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Concept
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Proteins
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Concept
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Repressor Proteins
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Concept
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Protein Structure, Quaternary
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Concept
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Protein Subunits
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Concept
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Cysteine Proteinase Inhibitors
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Concept
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Protein Structure, Tertiary
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Concept
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Viral Nonstructural Proteins
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Concept
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Phosphatidylethanolamine Binding Protein
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Concept
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Protein Structure, Secondary
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Concept
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Protein Folding
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Concept
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Protein Interaction Mapping
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Concept
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Databases, Protein
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Concept
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Recombinant Proteins
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Concept
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Protein Interaction Domains and Motifs
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Concept
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Protein Multimerization
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Concept
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Escherichia coli Proteins
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Concept
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Pore Forming Cytotoxic Proteins
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Concept
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Viral Regulatory and Accessory Proteins
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Concept
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Archaeal Proteins
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Academic Article
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The crystallographic structure of the aldose reductase-IDD552 complex shows direct proton donation from tyrosine 48.
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Academic Article
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Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding of cyclic imide inhibitors.
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Academic Article
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The membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus binds the dipeptide GlyMet via side chain interactions.
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Academic Article
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The crystal structure of Aq_328 from the hyperthermophilic bacteria Aquifex aeolicus shows an ancestral histone fold.
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Academic Article
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Activation of inhibitors by sortase triggers irreversible modification of the active site.
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Academic Article
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The 1.38 A crystal structure of DmsD protein from Salmonella typhimurium, a proofreading chaperone on the Tat pathway.
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Academic Article
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Raf kinase inhibitory protein function is regulated via a flexible pocket and novel phosphorylation-dependent mechanism.
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Academic Article
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Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism.
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Academic Article
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Time-controlled microfluidic seeding in nL-volume droplets to separate nucleation and growth stages of protein crystallization.
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Academic Article
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Structure of surface layer homology (SLH) domains from Bacillus anthracis surface array protein.
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Academic Article
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The crystal structures of the a-subunit of the a(2)ß (2) tetrameric Glycyl-tRNA synthetase.
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Academic Article
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Flexibility of the DNA-binding domains of trp repressor.
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Academic Article
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Crystal structure of trp repressor/operator complex at atomic resolution.
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Academic Article
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Bacillus anthracis inosine 5'-monophosphate dehydrogenase in action: the first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes.
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Academic Article
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A novel cofactor-binding mode in bacterial IMP dehydrogenases explains inhibitor selectivity.
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Academic Article
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Structure of Cryptosporidium IMP dehydrogenase bound to an inhibitor with in vivo antiparasitic activity.
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Academic Article
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Virtual high-throughput ligand screening.
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Academic Article
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The dimerization domain in DapE enzymes is required for catalysis.
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Academic Article
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Protein production for structural genomics using E. coli expression.
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Academic Article
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New aminopeptidase from "microbial dark matter" archaeon.
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Academic Article
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Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds.
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Academic Article
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Aromatic claw: A new fold with high aromatic content that evades structural prediction.
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Academic Article
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Insights into PG-binding, conformational change, and dimerization of the OmpA C-terminal domains from Salmonella enterica serovar Typhimurium and Borrelia burgdorferi.
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Academic Article
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Crystal structure of Bacillus subtilis YdaF protein: a putative ribosomal N-acetyltransferase.
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Academic Article
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Crystal structure of the novel PaiB transcriptional regulator from Geobacillus stearothermophilus.
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Academic Article
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A novel polyamine allosteric site of SpeG from Vibrio cholerae is revealed by its dodecameric structure.
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Academic Article
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Crystal structure of the novel PaiA N-acetyltransferase from Thermoplasma acidophilum involved in the negative control of sporulation and degradative enzyme production.
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Academic Article
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Substrate-Induced Allosteric Change in the Quaternary Structure of the Spermidine N-Acetyltransferase SpeG.
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Academic Article
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Protein surface analysis for function annotation in high-throughput structural genomics pipeline.
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Academic Article
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Inhibition of the dapE-Encoded N-Succinyl-L,L-diaminopimelic Acid Desuccinylase from Neisseria meningitidis by L-Captopril.
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Academic Article
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The dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase from Haemophilus influenzae contains two active-site histidine residues.
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Academic Article
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Structure of Calcarisporiella thermophila Hsp104 Disaggregase that Antagonizes Diverse Proteotoxic Misfolding Events.
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Academic Article
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Conserved residue His-257 of Vibrio cholerae flavin transferase ApbE plays a critical role in substrate binding and catalysis.
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Academic Article
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Structural and biochemical analysis of the metallo-ß-lactamase L1 from emerging pathogen Stenotrophomonas maltophilia revealed the subtle but distinct di-metal scaffold for catalytic activity.
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Academic Article
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Allosteric inhibitors of Mycobacterium tuberculosis tryptophan synthase.
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Academic Article
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Crystal structure of Nsp15 endoribonuclease NendoU from SARS-CoV-2.
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Academic Article
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SARS-CoV-2 Infection Severity Is Linked to Superior Humoral Immunity against the Spike.
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Academic Article
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Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2.
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Academic Article
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Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation.
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Academic Article
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Structural genomics and the Protein Data Bank.
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Academic Article
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2'-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography.
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Academic Article
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Catalytically impaired TrpA subunit of tryptophan synthase from Chlamydia trachomatis is an allosteric regulator of TrpB.
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Academic Article
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Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication.
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Academic Article
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Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2.
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Academic Article
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A Genomic Island of Vibrio cholerae Encodes a Three-Component Cytotoxin with Monomer and Protomer Forms Structurally Similar to Alpha-Pore-Forming Toxins.
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Academic Article
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Improved integration of single-cell transcriptome and surface protein expression by LinQ-View.
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Concept
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Protein Conformation, alpha-Helical
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Concept
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Protein Conformation, beta-Strand
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Grant
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THE MIDWEST CENTER FOR STRUCTURAL GENOMICS
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Grant
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The Midwest Center for Structural Genomics
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Grant
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The Midwest Center for Structural Genomics - Community Resource
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Grant
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Midwest Center for Structural Genomics
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Academic Article
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Sel1-like proteins and peptides are the major Oxalobacter formigenes-derived factors stimulating oxalate transport by human intestinal epithelial cells.
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Academic Article
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A high-throughput structural system biology approach to increase structure representation of proteins from Clostridioides difficile.
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